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SH2B1 promotes NSCLC cell proliferation through PI3K/Akt/mTOR signaling cascade
BACKGROUND: Non-small cell lung cancer (NSCLC), the most prevalent type of human lung cancer, is characterized by many molecular abnormalities. SH2B1, a member of the SH2-domain containing family, have recently been shown to act as tumor activators in multiple cancers. The objective of this study wa...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127928/ https://www.ncbi.nlm.nih.gov/pubmed/30202243 http://dx.doi.org/10.1186/s12935-018-0632-x |