SH2B1 promotes NSCLC cell proliferation through PI3K/Akt/mTOR signaling cascade

BACKGROUND: Non-small cell lung cancer (NSCLC), the most prevalent type of human lung cancer, is characterized by many molecular abnormalities. SH2B1, a member of the SH2-domain containing family, have recently been shown to act as tumor activators in multiple cancers. The objective of this study wa...

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Detalles Bibliográficos
Autores principales: Wang, Shaoqiang, Zheng, Yingying, He, Zhiwei, Zhou, Wolong, Cheng, Yuanda, Zhang, Chunfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127928/
https://www.ncbi.nlm.nih.gov/pubmed/30202243
http://dx.doi.org/10.1186/s12935-018-0632-x

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