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Systemic infection modifies the neuroinflammatory response in late stage Alzheimer’s disease

Clinical studies indicate that systemic infections accelerate cognitive decline in Alzheimer’s disease. Animal models suggest that this may be due to enhanced pro-inflammatory changes in the brain. We have performed a post-mortem human study to determine whether systemic infection modifies the neuro...

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Detalles Bibliográficos
Autores principales: Rakic, Sonja, Hung, Yat M. A., Smith, Matthew, So, Denise, Tayler, Hannah M., Varney, William, Wild, Joe, Harris, Scott, Holmes, Clive, Love, Seth, Stewart, William, Nicoll, James A. R., Boche, Delphine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127939/
https://www.ncbi.nlm.nih.gov/pubmed/30193587
http://dx.doi.org/10.1186/s40478-018-0592-3