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The role of RORα in salivary gland lesions in patients with primary Sjögren’s syndrome

BACKGROUND: The orphan nuclear receptors retinoic acid-related receptor α and γt (RORα and RORγt) are critical in the development of T helper 17 (Th17) cells, and ROR-specific synthetic ligands have proven efficacy in several mouse models of autoimmunity. However, the pathological significance of RO...

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Detalles Bibliográficos
Autores principales: Weng, Xiuhong, Liu, Yi, Cui, Shun, Cheng, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127992/
https://www.ncbi.nlm.nih.gov/pubmed/30189901
http://dx.doi.org/10.1186/s13075-018-1698-5