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The roles of aromatic residues in the glycine receptor transmembrane domain

BACKGROUND: Cys-loop receptors play important roles in fast neuronal signal transmission. Functional receptors are pentamers, with each subunit having an extracellular, transmembrane (TM) and intracellular domain. Each TM domain contains 4 α-helices (M1–M4) joined by loops of varying lengths. Many o...

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Detalles Bibliográficos
Autores principales: Tang, Bijun, Lummis, Sarah C. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127993/
https://www.ncbi.nlm.nih.gov/pubmed/30189850
http://dx.doi.org/10.1186/s12868-018-0454-8