Cargando…
Elevated contextual fear memory by SIRT6 depletion in excitatory neurons of mouse forebrain
A class of NAD-dependent protein deacetylases, the Sirtuin (SIRT) family of proteins is involved in aging, cell survival, and neurodegeneration. Recently, SIRT proteins, including SIRT6, have been reported to be important in learning and memory. However, the role of SIRT6 in excitatory brain neurons...
Autores principales: | Kim, Hyopil, Kim, Hyun-Seok, Kaang, Bong-Kiun |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127998/ https://www.ncbi.nlm.nih.gov/pubmed/30189861 http://dx.doi.org/10.1186/s13041-018-0391-6 |
Ejemplares similares
-
Conditional knock out of transcription factor CTCF in excitatory neurons induces cognitive deficiency
por: Choi, Dong Il, et al.
Publicado: (2021) -
Overexpression of activated CaMKII in the CA1 hippocampus impairs context discrimination, but not contextual conditioning
por: Ye, Sanghyun, et al.
Publicado: (2019) -
Abolished ketamine effects on the spontaneous excitatory postsynaptic current of medial prefrontal cortex neurons in GluN2D knockout mice
por: Han, Dae Hee, et al.
Publicado: (2021) -
Prior episode of colitis impairs contextual fear memory
por: Wu, Chia-Shan, et al.
Publicado: (2022) -
Increased social interaction in Shank2-deficient mice following acute social isolation
por: Choi, Ja Eun, et al.
Publicado: (2023)