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Amelioration of mitochondrial dysfunction in heart failure through S-sulfhydration of Ca(2+)/calmodulin-dependent protein kinase II
AIMS: Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) plays a critical role in the development of heart failure and in the induction of myocardial mitochondrial injury. Recent evidence has shown that hydrogen sulfide (H(2)S), produced by the enzyme cystathionine γ-lyase (CSE), improves the ca...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128039/ https://www.ncbi.nlm.nih.gov/pubmed/30195191 http://dx.doi.org/10.1016/j.redox.2018.08.008 |