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Amelioration of mitochondrial dysfunction in heart failure through S-sulfhydration of Ca(2+)/calmodulin-dependent protein kinase II

AIMS: Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) plays a critical role in the development of heart failure and in the induction of myocardial mitochondrial injury. Recent evidence has shown that hydrogen sulfide (H(2)S), produced by the enzyme cystathionine γ-lyase (CSE), improves the ca...

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Detalles Bibliográficos
Autores principales:	Wu, Dan, Hu, Qingxun, Tan, Bo, Rose, Peter, Zhu, Deqiu, Zhu, Yi Zhun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128039/ https://www.ncbi.nlm.nih.gov/pubmed/30195191 http://dx.doi.org/10.1016/j.redox.2018.08.008

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