A distinct class of antioxidant response elements is consistently activated in tumors with NRF2 mutations

NRF2 is a redox-responsive transcription factor that regulates expression of cytoprotective genes via its interaction with DNA sequences known as antioxidant response elements (AREs). NRF2 activity is induced by oxidative stress, but oxidative stress is not the only context in which NRF2 can be acti...

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Detalles Bibliográficos
Autores principales: Levings, Daniel C., Wang, Xuting, Kohlhase, Derek, Bell, Douglas A., Slattery, Matthew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128101/
https://www.ncbi.nlm.nih.gov/pubmed/30195190
http://dx.doi.org/10.1016/j.redox.2018.07.026

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128101/
https://www.ncbi.nlm.nih.gov/pubmed/30195190
http://dx.doi.org/10.1016/j.redox.2018.07.026

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