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Predictive biomarkers for response to EGFR-directed monoclonal antibodies for advanced squamous cell lung cancer
BACKGROUND: Upregulated expression and aberrant activation of the epidermal growth-factor receptor (EGFR) are found in lung cancer, making EGFR a relevant target for non-small-cell lung cancer (NSCLC). Treatment with anti-EGFR monoclonal antibodies (mAbs) is associated with modest improvement in ove...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128180/ https://www.ncbi.nlm.nih.gov/pubmed/29905778 http://dx.doi.org/10.1093/annonc/mdy196 |