NF-κB-Gasdermin D (GSDMD) Axis Couples Oxidative Stress and NACHT, LRR and PYD Domains-Containing Protein 3 (NLRP3) Inflammasome-Mediated Cardiomyocyte Pyroptosis Following Myocardial Infarction

BACKGROUND: Pyroptosis and oxidative stress play pivotal roles in cardiomyocyte loss after myocardial infarction. NF-κB is associated with oxidative stress and gasdermin D (GSDMD), the effector molecule of pyroptosis. However, the exact relationship between oxidative stress and cardiomyocyte pyropto...

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Detalles Bibliográficos
Autores principales: Lei, Qian, Yi, Tao, Chen, Can
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2018
Materias:
Animal Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128186/
https://www.ncbi.nlm.nih.gov/pubmed/30161099
http://dx.doi.org/10.12659/MSM.908529

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128186/
https://www.ncbi.nlm.nih.gov/pubmed/30161099
http://dx.doi.org/10.12659/MSM.908529

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