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The NF-κB Inhibitor, IMD-0354, Affects Immune Gene Expression, Bacterial Microbiota and Trypanosoma cruzi Infection in Rhodnius prolixus Midgut

Rhodnius prolixus is an insect vector of Trypanosoma cruzi, the causative agent of Chagas disease in Latin America. Nuclear factor-κB (NF-κB) transcription factors (TF) are conserved components of the innate immune system in several multicellular organisms including insects. The drug IMD-0354 [N-(3,...

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Detalles Bibliográficos
Autores principales: Vieira, Cecilia S., Moreira, Otacílio C., Batista, Kate K. S., Ratcliffe, Norman A., Castro, Daniele P., Azambuja, Patrícia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128222/
https://www.ncbi.nlm.nih.gov/pubmed/30233391
http://dx.doi.org/10.3389/fphys.2018.01189