Cargando…

The NF-κB Inhibitor, IMD-0354, Affects Immune Gene Expression, Bacterial Microbiota and Trypanosoma cruzi Infection in Rhodnius prolixus Midgut

Rhodnius prolixus is an insect vector of Trypanosoma cruzi, the causative agent of Chagas disease in Latin America. Nuclear factor-κB (NF-κB) transcription factors (TF) are conserved components of the innate immune system in several multicellular organisms including insects. The drug IMD-0354 [N-(3,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Vieira, Cecilia S., Moreira, Otacílio C., Batista, Kate K. S., Ratcliffe, Norman A., Castro, Daniele P., Azambuja, Patrícia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128222/ https://www.ncbi.nlm.nih.gov/pubmed/30233391 http://dx.doi.org/10.3389/fphys.2018.01189

Ejemplares similares

Cruzipain Promotes Trypanosoma cruzi Adhesion to Rhodnius prolixus Midgut
por: Uehara, Lívia Almeida, et al.
Publicado: (2012)

Impact of Trypanosoma cruzi on antimicrobial peptide gene expression and activity in the fat body and midgut of Rhodnius prolixus
por: Vieira, CS, et al.
Publicado: (2016)

Trypanosoma cruzi Immune Response Modulation Decreases Microbiota in Rhodnius prolixus Gut and Is Crucial for Parasite Survival and Development
por: Castro, Daniele P., et al.
Publicado: (2012)

Participation of Trypanosoma cruzi gp63 molecules on the interaction with Rhodnius prolixus
por: Rebello, Karina M., et al.
Publicado: (2019)

Bioluminescent imaging of Trypanosoma cruzi infection in Rhodnius prolixus
por: Henriques, Cristina, et al.
Publicado: (2012)

MDL28170, a Calpain Inhibitor, Affects Trypanosoma cruzi Metacyclogenesis, Ultrastructure and Attachment to Rhodnius prolixus Midgut
por: Ennes-Vidal, Vítor, et al.
Publicado: (2011)

RNA as a feasible marker of Trypanosoma cruzi viability during the parasite interaction with the triatomine vector Rhodnius prolixus (Hemiptera, Triatominae)
por: Finamore-Araujo, Paula, et al.
Publicado: (2022)

Effects of Infection by Trypanosoma cruzi and Trypanosoma rangeli on the Reproductive Performance of the Vector Rhodnius prolixus
por: Fellet, Maria Raquel, et al.
Publicado: (2014)

Enzymatic biosynthesis of B-complex vitamins is supplied by diverse microbiota in the Rhodnius prolixus anterior midgut following Trypanosoma cruzi infection
por: Tobias, Nicholas J., et al.
Publicado: (2020)

The effect of temperature increase on the development of Rhodnius prolixus and the course of Trypanosoma cruzi metacyclogenesis
por: Tamayo, Laura D., et al.
Publicado: (2018)

The novel NF-κB inhibitor IMD-0354 induces apoptosis in chronic lymphocytic leukemia
por: Kanduri, M, et al.
Publicado: (2011)

Trypanosoma cruzi TcSMUG L-surface Mucins Promote Development and Infectivity in the Triatomine Vector Rhodnius prolixus
por: Gonzalez, Marcelo S., et al.
Publicado: (2013)

Humoral responses in Rhodnius prolixus: bacterial feeding induces differential patterns of antibacterial activity and enhances mRNA levels of antimicrobial peptides in the midgut
por: Vieira, Cecilia Stahl, et al.
Publicado: (2014)

Rhodnius prolixus interaction with Trypanosoma rangeli: modulation of the immune system and microbiota population
por: Vieira, Cecilia S, et al.
Publicado: (2015)

Modulation of IMD, Toll, and Jak/STAT Immune Pathways Genes in the Fat Body of Rhodnius prolixus During Trypanosoma rangeli Infection
por: Rolandelli, Agustín, et al.
Publicado: (2021)

Enzootic Trypanosoma cruzi infection by Rhodnius prolixus shows transmission to humans and dogs in Vichada, Colombia
por: Cantillo-Barraza, Omar, et al.
Publicado: (2022)

Perimicrovillar membrane assembly: the fate of phospholipids synthesised by the midgut of Rhodnius prolixus
por: Bittencourt-Cunha, Paula Rêgo, et al.
Publicado: (2013)

Trypanosoma rangeli: a new perspective for studying the modulation of immune reactions of Rhodnius prolixus
por: Garcia, Eloi S, et al.
Publicado: (2009)

TcI/TcII co-infection can enhance Trypanosoma cruzi growth in Rhodnius prolixus
por: Araújo, Catarina A C, et al.
Publicado: (2014)

Trypanosoma cruzi-infected Rhodnius prolixus endure increased predation facilitating parasite transmission to mammal hosts
por: Marliére, Newmar Pinto, et al.
Publicado: (2021)

Selective IKK2 inhibitor IMD0354 disrupts NF-κB signaling to suppress corneal inflammation and angiogenesis
por: Lennikov, Anton, et al.
Publicado: (2018)

Influence of Serratia marcescens and Rhodococcus rhodnii on the Humoral Immunity of Rhodnius prolixus
por: Batista, Kate K. S., et al.
Publicado: (2021)

Trypanosoma rangeli infection impairs reproductive success of Rhodnius prolixus
por: Duarte da Silva, Bruna, et al.
Publicado: (2023)

Rhodnius prolixus Colonization and Trypanosoma cruzi Transmission in Oil Palm (Elaeis guineensis) Plantations in the Orinoco Basin, Colombia
por: Erazo, Diana, et al.
Publicado: (2020)

Rhodnius prolixus Hemolymph Immuno-Physiology: Deciphering the Systemic Immune Response Triggered by Trypanosoma cruzi Establishment in the Vector Using Quantitative Proteomics
por: Ouali, Radouane, et al.
Publicado: (2022)

Extracellular vesicles isolated from Trypanosoma cruzi affect early parasite migration in the gut of Rhodnius prolixus but not in Triatoma infestans
por: Paranaiba, Larissa F, et al.
Publicado: (2019)

Rhodnius prolixus: Identification of missing components of the IMD immune signaling pathway and functional characterization of its role in eliminating bacteria
por: Salcedo-Porras, Nicolas, et al.
Publicado: (2019)

Trypanosoma cruzi, Etiological Agent of Chagas Disease, Is Virulent to Its Triatomine Vector Rhodnius prolixus in a Temperature-Dependent Manner
por: Elliot, Simon L., et al.
Publicado: (2015)

Amino acids trigger down-regulation of superoxide via TORC pathway in the midgut of Rhodnius prolixus
por: Gandara, Ana Caroline P., et al.
Publicado: (2016)

High-Throughput Identification of the Rhodnius prolixus Midgut Proteome Unravels a Sophisticated Hematophagic Machinery
por: Ouali, Radouane, et al.
Publicado: (2020)

Elimination of Rhodnius prolixus in Central America
por: Hashimoto, Ken, et al.
Publicado: (2012)

Rhodnius prolixus uses the peptidoglycan recognition receptor rpPGRP-LC/LA to detect Gram-negative bacteria and activate the IMD pathway
por: Salcedo-Porras, Nicolas, et al.
Publicado: (2020)

Exposure to Trypanosoma parasites induces changes in the microbiome of the Chagas disease vector Rhodnius prolixus
por: Eberhard, Fanny E., et al.
Publicado: (2022)

Triflumuron Effects on the Physiology and Reproduction of Rhodnius prolixus Adult Females
por: Henriques, Bianca Santos, et al.
Publicado: (2016)

Studies on the treatment of melanoma with folate acid conjugated dextran and lauryl alcohol loaded with IMD0354
por: Liu, Can, et al.
Publicado: (2019)

New Cell Lines Derived from Laboratory Colony Triatoma infestans and Rhodnius prolixus, Vectors of Trypanosoma cruzi, Do Not Harbour Triatoma Virus
por: Penrice-Randal, Rebekah, et al.
Publicado: (2022)

Dynamics of maternal gene expression in Rhodnius prolixus
por: Pascual, Agustina, et al.
Publicado: (2022)

Differentiation of Rhodnius neglectus and Rhodnius prolixus (Hemiptera: Reduviidae: Triatominae) by multiple parameters
por: Falcone, Rossana, et al.
Publicado: (2020)

Draft Genome Sequence of Rhodococcus rhodnii Strain LMG5362, a Symbiont of Rhodnius prolixus (Hemiptera, Reduviidae, Triatominae), the Principle Vector of Trypanosoma cruzi
por: Pachebat, Justin A., et al.
Publicado: (2013)

New Antimicrobial Bioactivity against Multidrug-Resistant Gram-Positive Bacteria of Kinase Inhibitor IMD0354
por: Escobar, Iliana E, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_q0htm8mfp2rgreep3pgdn6d00o