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Dipeptidyl Peptidase‐4 Is a Pro‐Recovery Mediator During Acute Hepatotoxic Damage and Mirrors Severe Shifts in Kupffer Cells

Dipeptidyl peptidase‐4 (DPP‐4 or clusters of differentiation [CD]26) is a multifunctional molecule with established roles in metabolism. Pharmacologic inhibition of DPP‐4 is widely used to improve glycemic control through regulation of the incretin effect. Colaterally, CD26/DPP‐4 inhibition appears...

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Detalles Bibliográficos
Autores principales: Duarte, Nádia, Coelho, Inês, Holovanchuk, Denys, Inês Almeida, Joana, Penha‐Gonçalves, Carlos, Paula Macedo, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128231/
https://www.ncbi.nlm.nih.gov/pubmed/30202822
http://dx.doi.org/10.1002/hep4.1225