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Ratiometric Raman imaging reveals the new anti-cancer potential of lipid targeting drugs

De novo lipid synthesis is upregulated in cancer cells and inhibiting these pathways has displayed anti-tumour activity. Here we use Raman spectroscopy, focusing solely on high wavenumber spectra, to detect changes in lipid composition in single cells in response to drugs targeting de novo lipid syn...

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Detalles Bibliográficos
Autores principales: Jamieson, Lauren E., Wetherill, Corinna, Faulds, Karen, Graham, Duncan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128370/
https://www.ncbi.nlm.nih.gov/pubmed/30258563
http://dx.doi.org/10.1039/c8sc02312c