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p62 /SQSTM1 coding plasmid prevents age related macular degeneration in a rat model

P62/SQSTM1, a multi-domain protein that regulates inflammation, apoptosis, and autophagy, has been linked to age-related pathologies. For example, previously we demonstrated that administration of p62/SQSTM1-encoding plasmid reduced chronic inflammation and alleviated osteoporosis and metabolic synd...

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Detalles Bibliográficos
Autores principales: Kolosova, Nataliya G., Kozhevnikova, Oyuna S., Telegina, Darya V., Fursova, Anzhela Zh., Stefanova, Natalia A., Muraleva, Natalia A., Venanzi, Franco, Sherman, Michael Y., Kolesnikov, Sergey I., Sufianov, Albert A., Gabai, Vladimir L., Shneider, Alexander M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128417/
https://www.ncbi.nlm.nih.gov/pubmed/30153656
http://dx.doi.org/10.18632/aging.101537