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p62 /SQSTM1 coding plasmid prevents age related macular degeneration in a rat model
P62/SQSTM1, a multi-domain protein that regulates inflammation, apoptosis, and autophagy, has been linked to age-related pathologies. For example, previously we demonstrated that administration of p62/SQSTM1-encoding plasmid reduced chronic inflammation and alleviated osteoporosis and metabolic synd...
Autores principales: | Kolosova, Nataliya G., Kozhevnikova, Oyuna S., Telegina, Darya V., Fursova, Anzhela Zh., Stefanova, Natalia A., Muraleva, Natalia A., Venanzi, Franco, Sherman, Michael Y., Kolesnikov, Sergey I., Sufianov, Albert A., Gabai, Vladimir L., Shneider, Alexander M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128417/ https://www.ncbi.nlm.nih.gov/pubmed/30153656 http://dx.doi.org/10.18632/aging.101537 |
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