Impaired autophagic activity and ATG4B deficiency are associated with increased endoplasmic reticulum stress-induced lung injury.

Aging is the main risk factor for the development of idiopathic pulmonary fibrosis (IPF), a progressive and usually lethal lung disorder. Although the pathogenic mechanisms are uncertain, endoplasmic reticulum (ER) stress and impaired proteostasis that have been linked with aging are strongly associ...

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Detalles Bibliográficos
Autores principales: Maciel, Mariana, Hernández-Barrientos, Daniel, Herrera, Iliana, Selman, Moisés, Pardo, Annie, Cabrera, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128419/
https://www.ncbi.nlm.nih.gov/pubmed/30147026
http://dx.doi.org/10.18632/aging.101532

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128419/
https://www.ncbi.nlm.nih.gov/pubmed/30147026
http://dx.doi.org/10.18632/aging.101532

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