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Impact of demography and population dynamics on the genetic architecture of human longevity

The study of the genetics of longevity has been mainly addressed by GWASs that considered subjects from different populations to reach higher statistical power. The "price to pay" is that population-specific evolutionary histories and trade-offs were neglected in the investigation of gene-...

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Detalles Bibliográficos
Autores principales: Giuliani, Cristina, Sazzini, Marco, Pirazzini, Chiara, Bacalini, Maria Giulia, Marasco, Elena, Ruscone, Guido Alberto Gnecchi, Fang, Fang, Sarno, Stefania, Gentilini, Davide, Di Blasio, Anna Maria, Crocco, Paolina, Passarino, Giuseppe, Mari, Daniela, Monti, Daniela, Nacmias, Benedetta, Sorbi, Sandro, Salvarani, Carlo, Catanoso, Mariagrazia, Pettener, Davide, Luiselli, Donata, Ukraintseva, Svetlana, Yashin, Anatoliy, Franceschi, Claudio, Garagnani, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128422/
https://www.ncbi.nlm.nih.gov/pubmed/30089705
http://dx.doi.org/10.18632/aging.101515