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MicroRNA-221 silencing attenuates the degenerated phenotype of intervertebral disc cells

The aim of this study was to investigate the role of an antichondrogenic factor, MIR221 (miR-221), in intervertebral disc degeneration (IDD), and provide basic information for the development of a therapeutic strategy for the disc repair based on specific nucleic acid based drugs, such as miR-221 si...

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Detalles Bibliográficos
Autores principales: Penolazzi, Letizia, Lambertini, Elisabetta, Bergamin, Leticia Scussel, Roncada, Tosca, De Bonis, Pasquale, Cavallo, Michele, Piva, Roberta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128426/
https://www.ncbi.nlm.nih.gov/pubmed/30130742
http://dx.doi.org/10.18632/aging.101525