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GRSF1 suppresses cell senescence

A prominent phenotype triggered by the loss of mitochondrial homeostasis is cellular senescence, characterized by cessation of growth and a senescence-associated secretory phenotype (SASP). We identified the G-rich RNA sequence-binding factor 1 (GRSF1) as a major mitochondrial protein implicated in...

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Detalles Bibliográficos
Autores principales: Noh, Ji Heon, Kim, Kyoung Mi, Idda, M. Laura, Martindale, Jennifer L., Yang, Xiaoling, Abdelmohsen, Kotb, Gorospe, Myriam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128438/
https://www.ncbi.nlm.nih.gov/pubmed/30086537
http://dx.doi.org/10.18632/aging.101516