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Computing threshold antibody levels of protection in vaccine clinical trials: An assessment of methodological bias
In the development of new vaccines, understanding the level of vaccine-induced antibody that is sufficient to protect against disease can simplify and expedite the development and licensing process. If there is an accepted threshold antibody level that is indicative of protection, then smaller trial...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128451/ https://www.ncbi.nlm.nih.gov/pubmed/30192787 http://dx.doi.org/10.1371/journal.pone.0202517 |