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900MHz (1)H-/(13)C-NMR analysis of 2-hydroxyglutarate and other brain metabolites in human brain tumor tissue extracts
PURPOSE: To perform in vitro high-resolution 900 MHz magnetic resonance spectroscopy (NMR) analysis of human brain tumor tissue extracts and analyze for the oncometabolite 2-hydroxyglutarate (2HG) and other brain metabolites, not only for (1)H but also for (13)C with indirect detection by heteronucl...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128478/ https://www.ncbi.nlm.nih.gov/pubmed/30192797 http://dx.doi.org/10.1371/journal.pone.0203379 |