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900MHz (1)H-/(13)C-NMR analysis of 2-hydroxyglutarate and other brain metabolites in human brain tumor tissue extracts

PURPOSE: To perform in vitro high-resolution 900 MHz magnetic resonance spectroscopy (NMR) analysis of human brain tumor tissue extracts and analyze for the oncometabolite 2-hydroxyglutarate (2HG) and other brain metabolites, not only for (1)H but also for (13)C with indirect detection by heteronucl...

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Detalles Bibliográficos
Autores principales: Park, Gregory Hyung Jin, Yang, Seung-Ho, Baek, Hyeon-Man
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128478/
https://www.ncbi.nlm.nih.gov/pubmed/30192797
http://dx.doi.org/10.1371/journal.pone.0203379

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