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Influenza infection directly alters innate IL-23 and IL-12p70 and subsequent IL-17A and IFN-γ responses to pneumococcus in vitro in human monocytes

It is well accepted that influenza A virus predisposes individuals to often more severe superinfections with Streptococcus pneumonia. However, the mechanisms that lead to this synergy are not clearly understood. Recent data suggests that competent Th17 immunity is crucial to clearance and protection...

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Detalles Bibliográficos
Autores principales: Loughran, Sinead T., Power, Patrick A., Maguire, Paula T., McQuaid, Samantha L., Buchanan, Paul J., Jonsdottir, Ingileif, Newman, Robert W., Harvey, Ruth, Johnson, Patricia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128554/
https://www.ncbi.nlm.nih.gov/pubmed/30192848
http://dx.doi.org/10.1371/journal.pone.0203521