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Influenza infection directly alters innate IL-23 and IL-12p70 and subsequent IL-17A and IFN-γ responses to pneumococcus in vitro in human monocytes
It is well accepted that influenza A virus predisposes individuals to often more severe superinfections with Streptococcus pneumonia. However, the mechanisms that lead to this synergy are not clearly understood. Recent data suggests that competent Th17 immunity is crucial to clearance and protection...
Autores principales: | Loughran, Sinead T., Power, Patrick A., Maguire, Paula T., McQuaid, Samantha L., Buchanan, Paul J., Jonsdottir, Ingileif, Newman, Robert W., Harvey, Ruth, Johnson, Patricia A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128554/ https://www.ncbi.nlm.nih.gov/pubmed/30192848 http://dx.doi.org/10.1371/journal.pone.0203521 |
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