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Impact of storage conditions on the quality of nucleic acids in paraffin embedded tissues

RNA and DNA analyses from paraffin-embedded tissues (PET) are an important diagnostic tool for characterization of a disease, exploring biomarkers and treatment options. Since nucleic acids from formalin-fixed and paraffin-embedded (FFPE) tissue are of limited use for molecular analyses due to chemi...

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Detalles Bibliográficos
Autores principales: Groelz, Daniel, Viertler, Christian, Pabst, Daniela, Dettmann, Nadine, Zatloukal, Kurt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128582/
https://www.ncbi.nlm.nih.gov/pubmed/30192857
http://dx.doi.org/10.1371/journal.pone.0203608