Cargando…

Impaired hepatic amyloid-beta degradation in Alzheimer’s disease

Extensive research strongly suggests that amyloid beta (Aβ) aggregates in the brain have a central role in Alzheimer’s disease (AD) pathogenesis. Pathological Aβ deposition is likely due to an altered balance between overproduction and elimination. Rodent studies have suggested that the liver has a...

Descripción completa

Detalles Bibliográficos
Autores principales: Maarouf, Chera L., Walker, Jessica E., Sue, Lucia I., Dugger, Brittany N., Beach, Thomas G., Serrano, Geidy E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128628/
https://www.ncbi.nlm.nih.gov/pubmed/30192871
http://dx.doi.org/10.1371/journal.pone.0203659