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Impaired hepatic amyloid-beta degradation in Alzheimer’s disease

Extensive research strongly suggests that amyloid beta (Aβ) aggregates in the brain have a central role in Alzheimer’s disease (AD) pathogenesis. Pathological Aβ deposition is likely due to an altered balance between overproduction and elimination. Rodent studies have suggested that the liver has a...

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Detalles Bibliográficos
Autores principales:	Maarouf, Chera L., Walker, Jessica E., Sue, Lucia I., Dugger, Brittany N., Beach, Thomas G., Serrano, Geidy E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128628/ https://www.ncbi.nlm.nih.gov/pubmed/30192871 http://dx.doi.org/10.1371/journal.pone.0203659

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