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Phospholipid synthesis fueled by lipid droplets drives the structural development of poliovirus replication organelles

Rapid development of complex membranous replication structures is a hallmark of picornavirus infections. However, neither the mechanisms underlying such dramatic reorganization of the cellular membrane architecture, nor the specific role of these membranes in the viral life cycle are sufficiently un...

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Detalles Bibliográficos
Autores principales: Viktorova, Ekaterina G., Nchoutmboube, Jules A., Ford-Siltz, Lauren A., Iverson, Ethan, Belov, George A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128640/
https://www.ncbi.nlm.nih.gov/pubmed/30148882
http://dx.doi.org/10.1371/journal.ppat.1007280