Mitotic progression, arrest, exit or death relies on centromere structural integrity, rather than de novo transcription

Recent studies have challenged the prevailing dogma that transcription is repressed during mitosis. Transcription was also proposed to sustain a robust spindle assembly checkpoint (SAC) response. Here, we used live-cell imaging of human cells, RNA-seq and qPCR to investigate the requirement for de n...

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Detalles Bibliográficos
Autores principales: Novais-Cruz, Marco, Alba Abad, Maria, van IJcken, Wilfred FJ, Galjart, Niels, Jeyaprakash, A Arockia, Maiato, Helder, Ferrás, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128689/
https://www.ncbi.nlm.nih.gov/pubmed/30080136
http://dx.doi.org/10.7554/eLife.36898

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128689/
https://www.ncbi.nlm.nih.gov/pubmed/30080136
http://dx.doi.org/10.7554/eLife.36898

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