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RAP2 Mediates Mechano-responses of Hippo Pathway

Mammalian cells are surrounded by neighboring cells and extracellular matrix (ECM), which provide cells with structural support and mechanical cues that influence diverse biological processes(1). The Hippo pathway effectors YAP and TAZ are regulated by mechanical cues and mediate cellular responses...

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Detalles Bibliográficos
Autores principales: Meng, Zhipeng, Qiu, Yunjiang, Lin, Kimberly C., Kumar, Aditya, Placone, Jesse K., Fang, Cao, Wang, Kuei-Chun, Lu, Shicong, Pan, Margaret, Hong, Audrey W., Moroishi, Toshiro, Luo, Min, Plouffe, Steven W., Diao, Yarui, Ye, Zhen, Park, Hyun Woo, Wang, Xiaoqiong, Yu, Fa-Xing, Chien, Shu, Wang, Cun-Yu, Ren, Bing, Engler, Adam J., Guan, Kun-Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128698/
https://www.ncbi.nlm.nih.gov/pubmed/30135582
http://dx.doi.org/10.1038/s41586-018-0444-0