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New derivatives of hydrogenated pyrido[4,3-b]indoles as potential neuroprotectors: Synthesis, biological testing and solubility in pharmaceutically relevant solvents

The derivatives of hydrogenated pyrido[4,3-b]indoles as potential neuroprotectors have been synthesized. The different substituents were introduced into position 8 of the carboline fragment of the molecule: methyl-, methoxy-, fluorine- and chlorine-. Biological tests have shown that all the studied...

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Detalles Bibliográficos
Autores principales: Blokhina, Svetlana, Sharapova, Angelica, Ol'khovich, Marina, Ustinov, Anatoly, Perlovich, German
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128713/
https://www.ncbi.nlm.nih.gov/pubmed/30202220
http://dx.doi.org/10.1016/j.jsps.2018.04.003