Cargando…
New derivatives of hydrogenated pyrido[4,3-b]indoles as potential neuroprotectors: Synthesis, biological testing and solubility in pharmaceutically relevant solvents
The derivatives of hydrogenated pyrido[4,3-b]indoles as potential neuroprotectors have been synthesized. The different substituents were introduced into position 8 of the carboline fragment of the molecule: methyl-, methoxy-, fluorine- and chlorine-. Biological tests have shown that all the studied...
Autores principales: | Blokhina, Svetlana, Sharapova, Angelica, Ol'khovich, Marina, Ustinov, Anatoly, Perlovich, German |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128713/ https://www.ncbi.nlm.nih.gov/pubmed/30202220 http://dx.doi.org/10.1016/j.jsps.2018.04.003 |
Ejemplares similares
-
Experimental Examination of Solubility and Lipophilicity as Pharmaceutically Relevant Points of Novel Bioactive Hybrid Compounds
por: Sharapova, Angelica, et al.
Publicado: (2022) -
Isavuconazole: Thermodynamic Evaluation of Processes Sublimation, Dissolution and Partition in Pharmaceutically Relevant Media
por: Ol’khovich, Marina, et al.
Publicado: (2021) -
New Indole-3-Propionic Acid and 5-Methoxy-Indole Carboxylic Acid Derived Hydrazone Hybrids as Multifunctional Neuroprotectors
por: Anastassova, Neda, et al.
Publicado: (2023) -
Revisiting the Solubility–Permeability Relationship with Hydrophobic Drug Umifenovir in Pluronic Solutions: Impact of pH and Co-Solvent
por: Volkova, Tatyana, et al.
Publicado: (2023) -
The Gramine Route to Pyrido[4,3-b]indol-3-ones – Identification of a New Cytotoxic Lead
por: Wollein, Uwe, et al.
Publicado: (2011)