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Nanostructured liquid crystalline formulation as a remarkable new drug delivery system of anti-epileptic drugs for treating children patients

PURPOSE: Development of a new dosage-form of antiepileptic-drugs appropriated for children. METHODS: Clonazepam (Cl) was formulated as cubosomal-gel (cub-gel) to be used as a patch reservoir through transdermal-route. Cubosomes prepared using glycerol-mono-oleate(GMO)/Pluronic-F127(PF127) mixture. A...

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Detalles Bibliográficos
Autores principales: El-Enin, Hadel Abo, AL-Shanbari, Areej Hamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128721/
https://www.ncbi.nlm.nih.gov/pubmed/30202219
http://dx.doi.org/10.1016/j.jsps.2018.04.004