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Focused clamping of a single neuronal SNARE complex by complexin under high mechanical tension

Neuronal soluble N-ethylmaleimide-sensitive factor attachment protein receptors (SNAREs) catalyze synaptic vesicle fusion with presynaptic membranes through the formation of SNARE complexes. Complexin (Cpx) is the only presynaptic protein that tightly binds to SNAREs and regulates membrane fusion, b...

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Detalles Bibliográficos
Autores principales: Shon, Min Ju, Kim, Haesoo, Yoon, Tae-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128827/
https://www.ncbi.nlm.nih.gov/pubmed/30194295
http://dx.doi.org/10.1038/s41467-018-06122-3