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Sub-2 Å Ewald curvature corrected structure of an AAV2 capsid variant

Single-particle cryogenic electron microscopy (cryo-EM) provides a powerful methodology for structural biologists, but the resolutions typically attained with experimentally determined structures have lagged behind microscope capabilities. Here, we exploit several technical advances to improve resol...

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Detalles Bibliográficos
Autores principales: Tan, Yong Zi, Aiyer, Sriram, Mietzsch, Mario, Hull, Joshua A., McKenna, Robert, Grieger, Joshua, Samulski, R. Jude, Baker, Timothy S., Agbandje-McKenna, Mavis, Lyumkis, Dmitry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128836/
https://www.ncbi.nlm.nih.gov/pubmed/30194371
http://dx.doi.org/10.1038/s41467-018-06076-6