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Necroptosis mediates myofibre death in dystrophin-deficient mice

Duchenne muscular dystrophy (DMD) is a severe degenerative disorder caused by mutations in the dystrophin gene. Dystrophin-deficient muscles are characterised by progressive myofibre necrosis in which inflammation plays a deleterious role. However, the molecular mechanisms underlying inflammation-in...

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Detalles Bibliográficos
Autores principales: Morgan, Jennifer E., Prola, Alexandre, Mariot, Virginie, Pini, Veronica, Meng, Jinhong, Hourde, Christophe, Dumonceaux, Julie, Conti, Francesco, Relaix, Frederic, Authier, Francois-Jerôme, Tiret, Laurent, Muntoni, Francesco, Bencze, Maximilien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128848/
https://www.ncbi.nlm.nih.gov/pubmed/30194302
http://dx.doi.org/10.1038/s41467-018-06057-9