Dual action of L-Lactate on the activity of NR2B-containing NMDA receptors: from potentiation to neuroprotection

L-Lactate is a positive modulator of NMDAR-mediated signaling resulting in plasticity gene induction and memory consolidation. However, L-Lactate is also able to protect neurons against excito-toxic NMDAR activity, an indication of a mitigating action of L-Lactate on NMDA signaling. In this study, w...

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Detalles Bibliográficos
Autores principales: Jourdain, P., Rothenfusser, K., Ben-Adiba, C., Allaman, I., Marquet, P., Magistretti, P. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128851/
https://www.ncbi.nlm.nih.gov/pubmed/30194439
http://dx.doi.org/10.1038/s41598-018-31534-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128851/
https://www.ncbi.nlm.nih.gov/pubmed/30194439
http://dx.doi.org/10.1038/s41598-018-31534-y

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