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Dual action of L-Lactate on the activity of NR2B-containing NMDA receptors: from potentiation to neuroprotection
L-Lactate is a positive modulator of NMDAR-mediated signaling resulting in plasticity gene induction and memory consolidation. However, L-Lactate is also able to protect neurons against excito-toxic NMDAR activity, an indication of a mitigating action of L-Lactate on NMDA signaling. In this study, w...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128851/ https://www.ncbi.nlm.nih.gov/pubmed/30194439 http://dx.doi.org/10.1038/s41598-018-31534-y |