Novel analgesic ω-conotoxins from the vermivorous cone snail Conus moncuri provide new insights into the evolution of conopeptides

Cone snails are a diverse group of predatory marine invertebrates that deploy remarkably complex venoms to rapidly paralyse worm, mollusc or fish prey. ω-Conotoxins are neurotoxic peptides from cone snail venoms that inhibit Ca(v)2.2 voltage-gated calcium channel, demonstrating potential for pain ma...

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Detalles Bibliográficos
Autores principales: Sousa, Silmara R., McArthur, Jeffrey R., Brust, Andreas, Bhola, Rebecca F., Rosengren, K. Johan, Ragnarsson, Lotten, Dutertre, Sebastien, Alewood, Paul F., Christie, Macdonald J., Adams, David J., Vetter, Irina, Lewis, Richard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128854/
https://www.ncbi.nlm.nih.gov/pubmed/30194442
http://dx.doi.org/10.1038/s41598-018-31245-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128854/
https://www.ncbi.nlm.nih.gov/pubmed/30194442
http://dx.doi.org/10.1038/s41598-018-31245-4

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