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Mapping molecular landmarks of human skeletal ontogeny and pluripotent stem cell-derived articular chondrocytes

Tissue-specific gene expression defines cellular identity and function, but knowledge of early human development is limited, hampering application of cell-based therapies. Here we profiled 5 distinct cell types at a single fetal stage, as well as chondrocytes at 4 stages in vivo and 2 stages during...

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Detalles Bibliográficos
Autores principales: Ferguson, Gabriel B., Van Handel, Ben, Bay, Maxwell, Fiziev, Petko, Org, Tonis, Lee, Siyoung, Shkhyan, Ruzanna, Banks, Nicholas W., Scheinberg, Mila, Wu, Ling, Saitta, Biagio, Elphingstone, Joseph, Larson, A. Noelle, Riester, Scott M., Pyle, April D., Bernthal, Nicholas M., Mikkola, Hanna KA, Ernst, Jason, van Wijnen, Andre J., Bonaguidi, Michael, Evseenko, Denis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128860/
https://www.ncbi.nlm.nih.gov/pubmed/30194383
http://dx.doi.org/10.1038/s41467-018-05573-y