High HMGB1 levels in sputum are related to pneumococcal bacteraemia but not to disease severity in community-acquired pneumonia

During bacterial infections, damage-associated molecular patterns (DAMPs) and pathogen-associated molecular patterns (PAMPs) activate immune cells. Here, we investigated whether plasma and sputum levels of High Mobility Group Box 1 (HMGB1), a prototypic DAMP, are associated with disease severity and...

Descripción completa

Detalles Bibliográficos
Autores principales: Alpkvist, Helena, Athlin, Simon, Mölling, Paula, Norrby-Teglund, Anna, Strålin, Kristoffer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128869/
https://www.ncbi.nlm.nih.gov/pubmed/30194360
http://dx.doi.org/10.1038/s41598-018-31504-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128869/
https://www.ncbi.nlm.nih.gov/pubmed/30194360
http://dx.doi.org/10.1038/s41598-018-31504-4

Ejemplares similares