USP4 positively regulates RLR-induced NF-κB activation by targeting TRAF6 for K48-linked deubiquitination and inhibits enterovirus 71 replication

Retinoic acid-inducible gene I-like receptor (RLR) is one of the most important pattern recognition receptors of the innate immune system that detects positive and/or negative stranded RNA viruses. Subsequently, it stimulates downstream transcription of interferon regulatory factor 3 (IRF3) and nucl...

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Detalles Bibliográficos
Autores principales: Xu, Chao, Peng, Yang, Zhang, Qin, Xu, Xiao-Peng, Kong, Xiang-Min, Shi, Wei-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128947/
https://www.ncbi.nlm.nih.gov/pubmed/30194441
http://dx.doi.org/10.1038/s41598-018-31734-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128947/
https://www.ncbi.nlm.nih.gov/pubmed/30194441
http://dx.doi.org/10.1038/s41598-018-31734-6

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