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A cancer vaccine with dendritic cells differentiated with GM-CSF and IFNα and pulsed with a squaric acid treated cell lysate improves T cell priming and tumor growth control in a mouse model

[Image: see text] Introduction: Ovarian cancer is one of the most lethal gynecologic cancers. Relapses after remission are common, hence novel strategies are urgently needed. Our group has previously developed a vaccination approach based on dendritic cells pulsed with HOCl-oxidized tumor lysates. H...

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Detalles Bibliográficos
Autores principales: Mookerjee, Ananda, Graciotti, Michele, Kandalaft, Lana E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tabriz University of Medical Sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128972/
https://www.ncbi.nlm.nih.gov/pubmed/30211081
http://dx.doi.org/10.15171/bi.2018.24