Use of a temporary immersion bioreactor system for the sustainable production of thapsigargin in shoot cultures of Thapsia garganica

BACKGROUND: Thapsigargin and nortrilobolide are sesquiterpene lactones found in the Mediterranean plant Thapsia garganica L. Thapsigargin is a potent inhibitor of the sarco/endoplasmic reticulum calcium ATPase pump, inducing apoptosis in mammalian cells. This mechanism has been used to develop a tha...

Descripción completa

Detalles Bibliográficos
Autores principales: López, Carmen Quiñonero, Corral, Patricia, Lorrain-Lorrette, Bénédicte, Martinez-Swatson, Karen, Michoux, Franck, Simonsen, Henrik Toft
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128993/
https://www.ncbi.nlm.nih.gov/pubmed/30202426
http://dx.doi.org/10.1186/s13007-018-0346-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128993/
https://www.ncbi.nlm.nih.gov/pubmed/30202426
http://dx.doi.org/10.1186/s13007-018-0346-z

Ejemplares similares