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The Structural Basis of IKs Ion-Channel Activation: Mechanistic Insights from Molecular Simulations
Relating ion channel (iCh) structural dynamics to physiological function remains a challenge. Current experimental and computational techniques have limited ability to explore this relationship in atomistic detail over physiological timescales. A framework associating iCh structure to function is ne...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Biophysical Society
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6129186/ https://www.ncbi.nlm.nih.gov/pubmed/29874609 http://dx.doi.org/10.1016/j.bpj.2018.04.023 |