De novo NAD+ biosynthetic impairment in acute kidney injury in humans

Nicotinamide adenine dinucleotide (NAD+) extends longevity in experimental organisms, raising interest in its impact on human health. De novo NAD+ biosynthesis from tryptophan is evolutionarily conserved yet considered supplanted among higher species by biosynthesis from nicotinamide (Nam). Here we...

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Detalles Bibliográficos
Autores principales: Mehr, Ali Poyan, Tran, Mei T., Ralto, Kenneth M., Leaf, David E., Washco, Vaughan, Messmer, Joseph, Lerner, Adam, Kher, Ajay, Kim, Steven H., Khoury, Charbel C., Herzig, Shoshana J., Trovato, Mary E., Simon-Tillaux, Noemie, Lynch, Matthew R., Thadhani, Ravi I., Clish, Clary B., Khabbaz, Kamal R., Rhee, Eugene P., Waikar, Sushrut S., Berg, Anders H., Parikh, Samir M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6129212/
https://www.ncbi.nlm.nih.gov/pubmed/30127395
http://dx.doi.org/10.1038/s41591-018-0138-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6129212/
https://www.ncbi.nlm.nih.gov/pubmed/30127395
http://dx.doi.org/10.1038/s41591-018-0138-z

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