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Understanding the evolution of functional redundancy in metabolic networks
MOTIVATION: Metabolic networks have evolved to reduce the disruption of key metabolic pathways by the establishment of redundant genes/reactions. Synthetic lethals in metabolic networks provide a window to study these functional redundancies. While synthetic lethals have been previously studied in d...
Autores principales: | Sambamoorthy, Gayathri, Raman, Karthik |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6129275/ https://www.ncbi.nlm.nih.gov/pubmed/30423058 http://dx.doi.org/10.1093/bioinformatics/bty604 |
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