Comparative Network Reconstruction using mixed integer programming

MOTIVATION: Signal-transduction networks are often aberrated in cancer cells, and new anti-cancer drugs that specifically target oncogenes involved in signaling show great clinical promise. However, the effectiveness of such targeted treatments is often hampered by innate or acquired resistance due...

Descripción completa

Detalles Bibliográficos
Autores principales: Bosdriesz, Evert, Prahallad, Anirudh, Klinger, Bertram, Sieber, Anja, Bosma, Astrid, Bernards, René, Blüthgen, Nils, Wessels, Lodewyk F A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Eccb 2018: European Conference on Computational Biology Proceedings
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6129277/
https://www.ncbi.nlm.nih.gov/pubmed/30423075
http://dx.doi.org/10.1093/bioinformatics/bty616

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6129277/
https://www.ncbi.nlm.nih.gov/pubmed/30423075
http://dx.doi.org/10.1093/bioinformatics/bty616

Ejemplares similares